The Long and Short Non-coding RNAs in Cancer Biology



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Éditeur :

Springer


Collection :

Advances in Experimental Medicine and Biology

Paru le : 2016-07-04



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Description

The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.





Pages
458 pages
Collection
Advances in Experimental Medicine and Biology
Parution
2016-07-04
Marque
Springer
EAN papier
9789811014963
EAN EPUB
9789811014987

Informations sur l'ebook
Nombre pages copiables
4
Nombre pages imprimables
45
Taille du fichier
1382 Ko
Prix
147,69 €