Resistance to Photodynamic Therapy in Cancer

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Éditeur :

Springer


Collection :

Resistance to Targeted Anti-Cancer Therapeutics

Paru le : 2014-12-11

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Description
This volume provides a comprehensive review of resistance induced by photodynamic therapy (PDT) in tumor cells. Understanding the underlying mechanisms in this process leads to the improvement of therapeutic modality, in combination with chemotherapy, immunotherapy, and radiotherapy. Photodynamic therapy is a minimally invasive therapeutic procedure that can exert a selective or preferential cytotoxic activity toward malignant cells. The procedure involves administration of an intrinsically non-toxic photosensitizing agent (PS) followed by irradiation at a wavelength corresponding to a visible absorption band of the sensitizer. In the presence of oxygen, a series of events lead to direct tumor cell death, damage to the microvasculature, and induction of a local inflammatory reaction. Studies reveal that PDT can be curative, particularly in early stage tumors and this volume explores the potential of PDT, but also reveals strategic approaches to overcome resistance in tumor cells.
Pages
248 pages
Collection
Resistance to Targeted Anti-Cancer Therapeutics
Parution
2014-12-11
Marque
Springer
EAN papier
9783319127293
EAN EPUB
9783319127309

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
24
Taille du fichier
2580 Ko
Prix
94,94 €