Notch Signaling in Embryology and Cancer

Molecular Biology of Notch Signaling

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Éditeur :

Springer


Collection :

Advances in Experimental Medicine and Biology

Paru le : 2020-02-18



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Description

This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch’s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway’s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. 
Taken as a whole, with its companion books – Notch Signaling in Embryology and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors.  Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.



Pages
172 pages
Collection
Advances in Experimental Medicine and Biology
Parution
2020-02-18
Marque
Springer
EAN papier
9783030364212
EAN PDF
9783030364229

Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
17
Taille du fichier
6072 Ko
Prix
95,39 €
EAN EPUB
9783030364229

Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
17
Taille du fichier
18063 Ko
Prix
95,39 €