SARS-CoV-2 Spike Protein Convergent Evolution

Impact of Virus Variants on Efficacy of COVID-19 Therapeutics and Vaccines de

Éditeur :

Springer


Collection :

SpringerBriefs in Microbiology

Paru le : 2021-10-11

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Description

This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.
Pages
136 pages
Collection
SpringerBriefs in Microbiology
Parution
2021-10-11
Marque
Springer
EAN papier
9783030873233
EAN PDF
9783030873240

Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
13
Taille du fichier
2243 Ko
Prix
68,56 €
EAN EPUB
9783030873240

Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
13
Taille du fichier
4618 Ko
Prix
68,56 €