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This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. 

By focusing on the advances made over the last 30 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order to stimulate further research in new directions.
In the second version, fourteen chapters will be updated base on the most recent research articles. Ten new chapters will be added.
Pages
365 pages
Collection
n.c
Parution
2023-01-30
Marque
Springer
EAN papier
9789811974144
EAN PDF
9789811974151

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
36
Taille du fichier
13332 Ko
Prix
158,24 €
EAN EPUB
9789811974151

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
36
Taille du fichier
42486 Ko
Prix
158,24 €

Baoxue Yang is a professor and chairman of Department of Pharmacology at Peking University. Prof. Yang has been studying aquaporins for nearly 27 years and published more than 100 original research articles in related fields.

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