The Regulatory Genome in Adaptation, Evolution, Development, and Disease

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Éditeur :

Academic Press


Paru le : 2023-03-10

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Description
The Regulatory Genome in Adaptation, Evolution, Development, and Disease synthesizes insights from recent genomic and gene expression studies across organisms, from humans to plants, animals, and single cell life, exploring common roles gene regulation plays in adaptive evolution, developmental biology and susceptibility to disease. The book sheds light on gene regulation across evolutionary timelines, illuminating new areas of focus and future research. Chapters consider key elements in gene expression regulation, fundamentals of genomic alterations over time, and in response to environmental and local conditions, epigenetics in adaptive evolution, and adaptive gene regulation in healthy processes and developmental biology, and in disease biology. Throughout the book, a comparative approach is adopted across organisms to highlight common evolutionary themes and genome diversity revealed by recent sequencing and GWAS studies, as well as how this informs our understanding of human adaptive evolution. The book finishes by detailing how we can use this knowledge to impact disease outcomes and healthy human metabolism, development, and physiology. - Reviews key elements in the regulation of gene expression and modes of studying gene regulation across evolutionary timelines - Adopts a cross-species view, synthesizing recent sequencing and GWAS studies across organisms to draw out fresh meaning and highlight pathways for future research - Considers altered gene expression associated with developmental defects and disease, as well as healthy biology and physiology, and our adaptive response to disease influence
Pages
418 pages
Collection
n.c
Parution
2023-03-10
Marque
Academic Press
EAN papier
9780443153525
EAN PDF
9780443153532

Informations sur l'ebook
Nombre pages copiables
41
Nombre pages imprimables
41
Taille du fichier
3717 Ko
Prix
148,40 €
EAN EPUB SANS DRM
9780443153532

Informations sur l'ebook
Prix
148,40 €

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