Neurotrophic Natural Products



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Éditeur :

Springer


Paru le : 2024-02-10



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Description

This book deals with neurotrophins (NGF, BDNF, NT3, NT4), which can decrease cell death, induce differentiation, as well as sustain the structure and function of neurons. This makes neurotrophins potential therapeutic agents for the treatment of neurodegenerative disorders. However, these proteins have so far been ineffective in clinical trials mostly because they cannot pass the blood-brain barrier owing to their high-molecular weights. Consequently, small molecules that mimic neurotrophins and stimulate the synthesis of endogenous neurotrophins or enhance their neurotrophic actions are expected to be promising alternatives. Small-molecule natural products, which have been used in dietary functional foods or in traditional medicine over the course of human history, have potential to be developed as new therapeutic agents against neurodegenerative conditions such as Alzheimer’s disease. In this book, the authors introduce a variety of natural products possessing neurotrophic properties such as neurogenesis, neurite outgrowth promotion (neuritogenesis), and neuroprotection and focus on the chemistry and biology of several neurotrophic natural products.

Pages
473 pages
Collection
n.c
Parution
2024-02-10
Marque
Springer
EAN papier
9783031424212
EAN PDF
9783031424229

Informations sur l'ebook
Nombre pages copiables
4
Nombre pages imprimables
47
Taille du fichier
15606 Ko
Prix
179,34 €
EAN EPUB
9783031424229

Informations sur l'ebook
Nombre pages copiables
4
Nombre pages imprimables
47
Taille du fichier
118600 Ko
Prix
179,34 €


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