RNA as a Drug Target

The Next Frontier for Medicinal Chemistry de

,

Éditeur :

Wiley-VCH


Collection :

Methods & Principles in Medicinal Chemistry

Paru le : 2024-07-01

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Description

Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs
Existing paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug development process.
RNA as a Drug Target: The Next Frontier for Medicinal Chemistry offers a practice-oriented introduction to developing drug-like small molecules that selectively modulate both coding and non-coding RNAs. Beginning with a description and characterization of existing druggable RNAs, the book discusses how to approach different RNA targets for drug discovery. The result is a crucial resource for targeting RNAs and creating the next generation of life-saving pharmaceuticals.
RNA as a Drug Target readers will also find: A complete “toolbox” for working with RNA, from structure determination to screening and lead generation techniques A wide range of addressable targets and mechanisms, including splicing modulation, riboswitches, targeted degradation, and more Authoritative discussion of the potential of RNA-targeted small molecule therapeutics for drugging the epitranscriptome
RNA as a Drug Target provides an expert introduction to a new frontier in pharmaceutical research for medicinal chemists, biochemists, molecular biologists, and members of the pharmaceutical industry.
Pages
416 pages
Collection
Methods & Principles in Medicinal Chemistry
Parution
2024-07-01
Marque
Wiley-VCH
EAN papier
9783527351008
EAN PDF
9783527840434

Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
416
Taille du fichier
12206 Ko
Prix
160,99 €
EAN EPUB
9783527840441

Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
416
Taille du fichier
32973 Ko
Prix
137,15 €