Téléchargez le livre : Antibody Drug Conjugates

Antibody Drug Conjugates

Design, Discovery, and Development

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Éditeur :

Springer


Paru le : 2026-01-01



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Description

This volume ?provides a comprehensive recapitulation of structure-activity relationship (SAR) from a mechanism of action point of view for this unique therapeutic modality, in a largely disease agnostic manner. From a disease biology and pharmacology perspective, the cellular target and drug-conjugate selection, considerations on liker -chemistry and -antibody ratio, and formulation science and technology, to get from bench to bedside (i.e. from a laboratory to the systemic circulation in a patient). The book also provides an understanding around target binding and drug/"payload" release mechanisms. Furthermore, pharmacokinetic and safety pharmacological aspects from a regulatory and clinical perspective are discussed, along with current chemistry, manufacturing, controls guidance and emerging novel delivery devices or technologies.
 
The key differentiation in Antibody Drug Conjugates is the clinical and development discussion, that offers pragmatic considerations in medical product development, IP, regulatory considerations, among others. Furthermore, we discuss the topic as a platform, in a disease agnostic manner.
Pages
232 pages
Collection
n.c
Parution
2026-01-01
Marque
Springer
EAN papier
9783031893186
EAN PDF
9783031893193
Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
23
Taille du fichier
12268 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
128,17 €
EAN EPUB
9783031893193
Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
23
Taille du fichier
8591 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
128,17 €

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