Téléchargez le livre : Incorporation of Heterocycles into Combinatorial Chemistry

Incorporation of Heterocycles into Combinatorial Chemistry

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Springer


Collection :

SpringerBriefs in Molecular Science

Paru le : 2016-12-01

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Description
The author has summarized a decade of teaching combinatorial chemistry into this timely brief. The solid phase synthesis of unnatural heterocyclic alpha-amino acids is illustrated by practical examples starting from the ABCs of peptide synthesis explored in chapter one. Chapter two is concerned with the solid phase synthesis which is shown on various techniques – BillBoard, tea-bag, and Lantern devices, and demonstrated on heterocyclic examples and protocols. In the third chapter the tools for accelerating chemical synthesis – solid phase and liquid phase – are reviewed. Here the techniques of parallel refluxing (including microwave and flow technique) and parallel separation (filtration, centrifugation, evaporation, and chromatography) are described. In the chapters 4 and 5 the author goes on to describe how the liquid phase synthesis of heterocycles (reductive amination and Ugi reaction of heterocycles) is illustrated with the use of semi-automated protocols. Finally, the designof combinatorial libraries of heterocycles is reviewed including the original author’s findings.
Pages
117 pages
Collection
SpringerBriefs in Molecular Science
Parution
2016-12-01
Marque
Springer
EAN papier
9783319500133
EAN PDF
9783319500157
Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
11
Taille du fichier
6932 Ko
Prix
52,74 €
EAN EPUB
9783319500157
Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
11
Taille du fichier
3543 Ko
Prix
52,74 €

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