Téléchargez le livre : Resistance of Cancer Cells to CTL-Mediated Immunotherapy

Resistance of Cancer Cells to CTL-Mediated Immunotherapy

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Springer


Paru le : 2015-06-20

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Description
This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, proteasome inhibitors, Bcl-2 family inhibitors, PARP, antibodies, and more.
Pages
353 pages
Collection
n.c
Parution
2015-06-20
Marque
Springer
EAN papier
9783319178066
EAN PDF
9783319178073
Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
35
Taille du fichier
7209 Ko
Prix
94,94 €
EAN EPUB
9783319178073
Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
35
Taille du fichier
2734 Ko
Prix
94,94 €

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