Inflammasome Signaling and Bacterial Infections

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Éditeur :

Springer


Collection :

Current Topics in Microbiology and Immunology

Paru le : 2016-07-26

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Description

This volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and highlights their action, in particular in response to infection with important bacterial model organisms and the corresponding disease pathologies. The first chapters review new insights into the assembly and structures of inflammasome components and emphasize general strategies of up- and downstream signaling events. In addition, the authors specifically discuss the composition and activity of inflammasomes during infection with various gut pathogens (Salmonella, Shigella, Yersinia, Listeria and Helicobacter), respiratory pathogens (Mycobacterium, Legionella, Burkholderia and Streptococcus) as well as skin and soft tissue pathogens (Francisella and Staphylococcus). The discoveries presented provide a better understanding of the cellular and molecular biology of inflammasomes, which will pinpoint important new therapeutic targets for the treatment and prevention of multiple infectious diseases in the future. It is a valuable resource for students, scientists and clinicians, providing up-to-date information on this emerging research topic.
Pages
282 pages
Collection
Current Topics in Microbiology and Immunology
Parution
2016-07-26
Marque
Springer
EAN papier
9783319411705
EAN PDF
9783319411712

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
28
Taille du fichier
5478 Ko
Prix
147,69 €
EAN EPUB
9783319411712

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
28
Taille du fichier
2355 Ko
Prix
147,69 €