Cell Signaling During Mammalian Early Embryo Development



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Springer


Collection :

Advances in Experimental Medicine and Biology

Paru le : 2015-05-08



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Description
The book considers signaling events from the zygote embryo through to the blastocyst with relevant data from embryonic stem (ES) cells, including dialogue with the extracellular environment and with the maternal tract during the implantation process. Application of the knowledge described to improve the success of human and animal assisted conception is considered where appropriate, but the focus is largely on fundamental rather than applied cell/molecular biology, as this is the area that has historically been neglected. While the general features of metabolism during preimplantation development are well established, especially in terms of nutrient requirements, uptake and fate, remarkably little is known about early embryo signaling events, intracellular or intercellular, between individual embryos in vitro or with the female reproductive tract in vivo. This contrasts with the wealth of information on cell signaling in somatic cells and tissues, as a glance at any textbook of biochemistry illustrates. This lack of information is such that our understanding of the molecular cell biology of early embryos -- a prerequisite to defining the mechanisms which regulate development at this critical stage of the life cycle -- is seriously incomplete. This volume is the first to address this issue by describing the current state of knowledge on cell signaling during mammalian early embryo development and highlighting priority areas for research.
Pages
216 pages
Collection
Advances in Experimental Medicine and Biology
Parution
2015-05-08
Marque
Springer
EAN papier
9781493924790
EAN PDF
9781493924806

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
21
Taille du fichier
5407 Ko
Prix
94,94 €
EAN EPUB
9781493924806

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
21
Taille du fichier
1495 Ko
Prix
94,94 €