P. Michael Conn is the Senior Vice President for Research and Associate Provost, Texas Tech Health Sciences Center. He is The Robert C. Kimbrough, Professor of Internal Medicine and Cell Biology/Biochemistry. He was previously Director of Research Advocacy and Professor of Physiology and Pharmacology, Cell Biology and Development and Obstetrics and Gynecology at Oregon Health and Science University and Senior Scientist of the Oregon National Primate Research Center (ONPRC). He served for twelve years as Special Assistant to the President and Associate Director of the ONPRC. After receiving a B.S. degree and teaching certification from the University of Michigan (1971), a M.S. from North Carolina State University (1973), and a Ph.D. degree from Baylor College of Medicine (1976), Conn did a fellowship at the NIH, then joined the faculty in the Department of Pharmacology, Duke University Medical Center where he was promoted to Associate Professor in 1982. In 1984, he became Professor and Head of Pharmacology at the University of Iowa College of Medicine, a position he held for eleven years. Conn is known for his research in the area of the cellular and molecular basis of action of gonadotropin releasing hormone action in the pituitary and therapeutic approaches that restore misfolded proteins to function. His work has led to drugs that have benefitted humans and animals. Most recently, he has identified a new class of drugs, pharmacoperones, which act by regulating the intracellular trafficking of receptors, enzymes and ion channels. He has authored or co-authored over 350 publications in this area and written or edited over 200 books, including texts in neurosciences, molecular biology and endocrinology. Conn has served as the editor of many professional journals and book series (Endocrinology, Journal of Clinical Endocrinology and Metabolism, Endocrine, Methods, Progress in Molecular Biology and Translational Science and Contemporary Endocrinology). Conn served on the National Board of Medical Examiners, including two years as chairman of the reproduction and endocrinology committee. The work of his laboratory has been recognized with a MERIT award from the NIH, the J.J. Abel Award of the American Society for Pharmacology and Experimental Therapeutics, the Weitzman, Oppenheimer and Ingbar Awards of the Endocrine Society, the National Science Medal of Mexico (the Miguel Aleman Prize) and the Stevenson Award of Canada. He is the recipient of the Oregon State Award for Discovery, the Media Award of the American College of Neuropsychopharmacology and was named a distinguished Alumnus of Baylor College of Medicine in 2012. Conn is a previous member of Council for the American Society for Cell Biology and the Endocrine Society and is a prior President of the Endocrine Society, during which time he founded the Hormone Foundation and worked with political leadership to heighten the public’s awareness of diabetes. Conn’s students and fellows have gone on to become leaders in industry and academia. He is an elected member of the Mexican Institute of Medicine and a fellow of the American Association for the Advancement of Science. He is the co-author of The Animal Research War (2008) and many articles for the public and academic community on the value of animal research and the dangers posed by animal extremism. His op/eds have appeared in The Washington Post, The LA Times, The Wall Street Journal, the Des Moines Register, and elsewhere. Conn consults with organizations that are influenced by animal extremism and with universities and companies facing challenges from these groups.
Télécharger le livre :  Conn's Handbook of Models for Human Aging

Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated...
Editeur : Academic Press
Parution : 2018-04-05

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Télécharger le livre :  Animal Models for the Study of Human Disease

Animal Models for the Study of Human Disease, Second Edition, provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy researchers across biomedical and...
Editeur : Academic Press
Parution : 2017-06-20

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Télécharger le livre :  Conn's Translational Neuroscience

Conn's Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain...
Editeur : Academic Press
Parution : 2016-09-28

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Télécharger le livre :  Electrophysiology and Microinjection

Electrical activity is central to the functioning and nature of neural cells. Every effort has been made in this volume to provide representative examples of useful techniques that have made this area a productive component of the neurosciences.Convenient bench-top...
Editeur : Academic Press
Parution : 2016-07-02

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Télécharger le livre :  Methods in Neurosciences

Because of the significance of morphology and cellular communication unique to the functioning and interdependence of neural systems, many of the advances in the neurosciences rely on classic as well as new microscopy techniques.A convenient bench-top format**Methods...
Editeur : Academic Press
Parution : 2016-07-02

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Télécharger le livre :  The Receptors

The Receptors, Volume III deals with receptors for interferons, hormones, and growth factors as well as for ?-aminobutyric acid, tuftsin, somatomedin, and insulin. Prolactin and nicotine receptors are also considered, along with the protein tyrosine kinase activity of...
Editeur : Academic Press
Parution : 2014-05-10

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Télécharger le livre :  The Receptors

The Receptors, Volume IV deals with receptors for intracellular hormones, estrogen, and sex steroids as well as for dopamine, cholecystokinin, and corticotropin.The role of surface recognition receptors in disease is also discussed, along with receptors for plant auxin...
Editeur : Academic Press
Parution : 2014-05-10

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Télécharger le livre :  The Receptors

The Receptors, Volume II deals with receptors for somatostatin, vitamin D, insulin, and animal viruses, as well as for the ?2-adrenergic and Ah systems.The significance of translational modifications of receptor ligands is discussed, along with the mechanisms of...
Editeur : Academic Press
Parution : 2014-05-10

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Télécharger le livre :  Gene Probes

Methods in Neurosciences, Volume 1: Gene Probes is a compendium of papers that deals with the developments in molecular biology, cell biology, and electrophysiology. Section I deals with gene expression using the Xenopus Oocyte system for expression and cloning of...
Editeur : Academic Press
Parution : 2014-04-24

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Télécharger le livre :  Fluorescence Microscopy

Fluorescence Microscopy: Super-Resolution and other Novel Techniques delivers a comprehensive review of current advances in fluorescence microscopy methods as applied to biological and biomedical science. With contributions selected for clarity, utility, and...
Editeur : Academic Press
Parution : 2014-02-24

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124,49

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Télécharger le livre :  Cellular Endocrinology in Health and Disease

Cellular Endocrinology in Health and Disease describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell...
Editeur : Academic Press
Parution : 2014-02-12

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Télécharger le livre :  Endosome Signaling Part B

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field.This is the second of two volumes on endosome signaling and includes chapters on such topics as measurement of entry into the...
Editeur : Academic Press
Parution : 2013-12-26

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Télécharger le livre :  Endosome Signaling Part A

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field.This is the first of two volumes on endosome signaling and includes chapters on such topics as measurement of entry into the...
Editeur : Academic Press
Parution : 2013-12-17

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Télécharger le livre :  Neuropeptide Technology

Methods in Neurosciences, Volume 6: Neuropeptide Technology: Synthesis, Assay, Purification, and Processing describes procedures and tools of assay useful for the identification, purification, and quantification of neuropeptides and their receptors. This volume is...
Editeur : Academic Press
Parution : 2013-10-22

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Télécharger le livre :  Receptors

Methods in Neurosciences, Volume 11: Receptors: Model Systems and Specific Receptors is a compilation of papers that describes techniques and information that are important to the neurosciences. This volume discusses preferred receptor techniques, molecular techniques,...
Editeur : Academic Press
Parution : 2013-10-22

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Télécharger le livre :  Cell Culture

Methods in Neurosciences, Volume 3: Quantitative and Qualitative Microscopy is a collection of papers that deals with microscopic techniques in statistical measures. This volume describes microscopy using sophisticated stains and dyes to advance observation of tests...
Editeur : Academic Press
Parution : 2013-10-22

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Télécharger le livre :  Methods in Neurosciences

Methods in Neurosciences, Volume 4: Electrophysiology and Microinjection is a collection of papers that deals with the electrically excitability feature of many cell types. This volume describes the characteristic features of some nervous tissue to conduct signals...
Editeur : Academic Press
Parution : 2013-10-22

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Télécharger le livre :  Neurobiology of Cytokines, Part B

Recent data suggest a critical role for cytokines in the regulation of brain and endocrine function under normal physiological conditions. The aim of this volume and its companion Volume 16 is to provide an overview of the effects of cytokines in the brain and in the...
Editeur : Academic Press
Parution : 2013-10-22

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Télécharger le livre :  Pulsatility in Neuroendocrine Systems

Pulsatility is now recognized as a nearly ubiquitous functional feature of neuroendocrine systems. This volume presents a comprehensive guide to the established and emerging technologies being used to study the perplexing phenomenon of pulsatility. Molecular, cellular,...
Editeur : Academic Press
Parution : 2013-10-22

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Télécharger le livre :  Lipid Metabolism in Signaling Systems

Many of the phospholipases and even the receptor for inositol 1,4,5-trisphosphate have recently been cloned and sequenced and play an important role in neurotransmission. Methods developed in recent years for the study of the enzymes and intermediates involved in the...
Editeur : Academic Press
Parution : 2013-10-22

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